2008年
2008年発表論文
Hikata T, Takaishi H, Takito J, Hakozaki A, Furukawa M, Uchikawa S,
Kimura T, Okada Y, Matsumoto M, Yoshimura A, Nishimura R, Reddy SV,
Asahara H, Toyama Y. PIAS3 negatively regulates RANKL-mediated
osteoclastogenesis directly in osteoclast precursors and indirectly via
osteoblasts. Blood. 2008 Oct 24. [Epub ahead of print]
Sanada T, Takaesu G, Mashima R, Yoshida R, Kobayashi T, Yoshimura
A. FLN29 deficiency reveals its negative regulatory role in the
Toll-like receptor (TLR) and retinoic acid-inducible gene I
(RIG-I)-like helicases signaling pathway.
J Biol Chem. 2008 Oct 10. [Epub ahead of print]
Miyamoto K, Miyamoto T, Kato R, Yoshimura A, Motoyama N, Suda T.
FoxO3a regulates hematopoietic homeostasis through a negative feedback
pathway in conditions of stress or aging.
Blood. 2008 Sep 17. [Epub ahead of print]
Sitko JC, Yeh B, Kim M, Zhou H, Takaesu G, Yoshimura A, McBride WH,
Jewett A, Jamieson CA, Cacalano NA. SOCS3 regulates p21 expression and
cell cycle arrest in response to DNA damage.
Cell Signal. 2008 Aug 23. [Epub ahead of print]
Ikeda O, Sekine Y, Muromoto R, Ohbayashi N, Yoshimura A, Matsuda
T.
Enhanced c-Fms/M-CSF receptor signaling and wound-healing process in
bone marrow-derived macrophages of signal-transducing adaptor protein-2
(STAP-2) deficient mice.
Biol Pharm Bull. 2008 Sep;31(9):1790-3.
Zhang R, Dhillon H, Yin H, Yoshimura A, Lowell BB, Maratos-Flier E,
Flier JS. Selective inactivation of Socs3 in SF1 neurons improves
glucose homeostasis without affecting body weight.
Endocrinology. 2008 Nov;149(11):5654-61.
Shiraishi H, Yoshida H, Saeki K, Miura Y, Watanabe S, Ishizaki T,
Hashimoto M, Takaesu G, Kobayashi T, Yoshimura A. Prostaglandin
E2 is a major soluble factor produced by stromal cells for preventing
inflammatory cytokine production from dendritic cells.
Int Immunol. 2008 Sep;20(9):1219-29. Epub 2008 Jul 17.
Ozawa Y, Nakao K, Kurihara T, Shimazaki T, Shimmura S, Ishida S,
Yoshimura A, Tsubota K, Okano H. Roles of STAT3/SOCS3 pathway in
regulating the visual function and ubiquitin-proteasome-dependent
degradation of rhodopsin during retinal inflammation.
J Biol Chem. 2008 Sep 5;283(36):24561-70.
Ikeda O, Sekine Y, Yasui T, Oritani K, Sugiyma K, Muromoto R, Ohbayashi
N, Yoshimura A, Matsuda T. STAP-2 negatively regulates both canonical
and noncanonical NF-kappaB activation induced by Epstein-Barr
virus-derived latent membrane protein 1.
Mol Cell Biol. 2008 Aug;28(16):5027-42.
Haffner MC, Jurgeit A, Berlato C, Geley S, Parajuli N, Yoshimura A,
Doppler W. Interaction and functional interference of glucocorticoid
receptor and SOCS1. J Biol Chem. 2008 283(32):22089-96.
Ichiyama K, Yoshida H, Wakabayashi Y, Chinen T, Saeki K, Nakaya M,
Takaesu G, Hori S, Yoshimura A, Kobayashi T. Foxp3 inhibits
RORgammat-mediated IL-17A mRNA transcription through direct interaction
with RORgammat. J Biol Chem. 2008 Jun
20;283(25):17003-8.
Takaki H, Ichiyama K, Koga K, Chinen T, Takaesu G, Sugiyama Y, Kato S,
Yoshimura A, Kobayashi T. STAT6 inhibits TGF-beta 1-mediated Foxp3
induction through direct binding to the Foxp3 promoter, which is
reverted by retinoic acid receptor. J Biol Chem. 2008 May
30;283(22):14955-62
Torisu T, Nakaya M, Watanabe S, Hashimoto M, Yoshida H, Chinen T,
Yoshida R, Okamoto F, Hanada T, Torisu K, Takaesu G, Kobayashi T,
Yasukawa H, Yoshimura A. Suppressor of cytokine signaling 1 protects
mice against concanavalin A-induced hepatitis by inhibiting apoptosis.
Hepatology. 2008 Jan 14;47(5):1644-1654
Horino J, Fujimoto M, Terabe F, Serada S, Takahashi T, Soma Y, Tanaka
K, Chinen T, Yoshimura A, Nomura S, Kawase I, Hayashi N, Kishimoto T,
Naka T. Suppressor of cytokine signaling-1 ameliorates dextran sulfate
sodium-induced colitis in mice. Int Immunol. 2008
Jun;20(6):753-62.
Tanaka K, Ichiyama K, Hashimoto M, Yoshida H, Takimoto T, Takaesu G,
Torisu T, Hanada T, Yasukawa H, Fukuyama S, Inoue H, Nakanishi Y,
Kobayashi T, Yoshimura A. Loss of Suppressor of Cytokine Signaling 1 in
Helper T Cells Leads to Defective Th17 Differentiation by Enhancing
Antagonistic Effects of IFN-{gamma} on STAT3 and Smads. J Immunol. 2008
Mar 15;180(6):3746-56.
Aki D, Minoda Y, Yoshida H, Watanabe S, Yoshida R, Takaesu G, Chinen T,
Inaba T, Hikida M, Kurosaki T, Saeki K, Yoshimura A. Peptidoglycan and
lipopolysaccharide activate PLCgamma2, leading to enhanced cytokine
production in macrophages and dendritic cells. Genes Cells. 2008
Feb;13(2):199-208.
Zhu BM, Ishida Y, Robinson GW, Pacher-Zavisin M, Yoshimura A, Murphy
PM, Hennighausen L. SOCS3 negatively regulates the gp130-STAT3 pathway
in mouse skin wound healing. J Invest Dermatol. 2008
Jul;128(7):1821-9
Ryo A, Tsurutani N, Ohba K, Kimura R, Komano J, Nishi M, Soeda H,
Hattori S, Perrem K, Yamamoto M, Chiba J, Mimaya J, Yoshimura K,
Matsushita S, Honda M, Yoshimura A, Sawasaki T, Aoki I, Morikawa Y,
Yamamoto N. SOCS1 is an inducible host factor during HIV-1 infection
and regulates the intracellular trafficking and stability of HIV-1 Gag.
Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):294-9.
Yoshimura T, Sonoda KH, Miyazaki Y, Iwakura Y, Ishibashi T, Yoshimura
A, Yoshida H. Differential roles for IFN-{gamma} and IL-17 in
experimental autoimmune uveoretinitis. Int Immunol. 2008
Feb;20(2):209-14
Sugiyama N, Nakashima H, Yoshimura T, Sadanaga A, Shimizu S, Masutani
K, Igawa T, Akahoshi M, Miyake K, Takeda A, Yoshimura A, Hamano S,
Yoshida H. Amelioration of human lupus-like phenotypes in MRL/lpr mice
by overexpression of IL-27R{alpha} (WSX-1). Ann Rheum Dis. 2008 in
press
Yu Q, Minoda Y, Yoshida R, Yoshida H, Iha H, Kobayashi T, Yoshimura A,
Takaesu G. HTLV-1 Tax-mediated TAK1 activation involves TAB2 adapter
protein. Biochem Biophys Res Commun. 2008 Jan 4;365(1):189-94.